Maintaining optimal levels of glutathione appears to be important for supporting cognitive function, especially as we age.* The normal process of aging is associated with a decrease in glutathione regulation, which can result in increased oxidative activity.* Less than optimum levels of glutathione are observed in individuals experiencing a decline in cognitive function.* Conversely, individuals living over 100 years tend to have higher glutathione reductase activity.* A common mistaken belief is that glutathione is not well absorbed when its taken orally, but significant data confirms it is efficiently absorbed across the intestinal epithelium by a specific uptake system.* Glutathione-SR from Thorne Research represents an important breakthrough in glutathione supplementation
For a supplement to be effective, it must be designed to survive the digestive tract and reach the cells intact
Glutathione reductase and glutathione peroxidase (GSH-Px) activities were measured using GSSG/NADPH and cumene hydroperoxide as substrates respectively as described previously (Raza et al., 2004
Tian Y, et al
The form of the peptide, the amount used, and the surrounding formulation can vary considerably from product to product, warns Saldarriaga
10.1016/j.gie.2017.05.036 13 AlonsoJ.PetukhovaM.VilagutG.ChatterjiS.HeeringaS.stnT