N32A showed a ~ 18-fold increase in the K M for carnitine and N210A a ~11-fold increase (Fig
h , Volcano plots of the fold change in mitochondrial metabolite abundance (log 2 ) versus P values (-log) from HEK-293T SLC25A39 knockout cell line expressing a vector control or SLC25A40 cDNA
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Exposure to viruses, bacteria, radiation, environmental toxins, and pollution may deplete glutathione levels, resulting in a buildup of free radicals, which are unstable atoms that can be extremely harmful to the body (Lang et al., 1992)