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The nausea happens for several reasons

It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]

Subcutaneous injection delivers the peptide directly into tissue where it can exert systemic effects

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Ambery P, Parker VE, Stumvoll M, Posch MG, Heise T, Plum-Moerschel L, et al

In two different studies, trial participants were given fatty acids with a meal, before and after supplementing their diet with L-carnitine (3g/day) for ten days