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Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

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The FLOW trial for semaglutide kidney outcomes in T2DM halted due to interim results meeting efficacy criteria FLOW is a RCT comparing injectable semaglutide 1.0 mg with placebo as an adjunct to standard of care on kidney outcomes in people with type 2 diabetes and chronic kidney disease

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