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MCP-1 (monocyte chemoattractant protein-1) staining intensitya neuroinflammation biomarkerwas significantly reduced in treated animals, indicating effective downregulation of chemokine-related immune activation

While some patients have reported weight loss, these effects vary from person to person and are not guaranteed

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Stay at least two inches (around 5cm) clear of the navel, which the NHS guidance recommends avoiding

A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]