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Acute pancreatitis can be caused by gallstones or bile duct stones when they block the tubes leading from the pancreas to the stomach, which can be caused by rapid weight loss 28

However, both medications can independently affect the gastrointestinal system , which warrants consideration

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It is also worth noting that while semaglutide has not been linked to an increased risk of cancer, people with type 2 diabetes have an increased risk of developing certain types of cancer, such as liver and pancreatic cancer

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Incretin-based therapies for type 2 diabetes mellitus