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While BIO89-100 has been reported to be a balanced agonist of FGF21s receptors in vitro , the smaller magnitude of effect on adiponectin compared to efruxifermin suggest that BIO89-100 may not have maximally stimulated FGFR1c signaling in adipose tissue at the doses tested in humans ( Figure 3B )
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It is designed to maintain sample integrity and reduce contamination risk during repeated withdrawals in laboratory applications
It is commonly used off-label in oral form to support hair health, and is believed to increase blood flow to hair follicles and extend the hair growth (anagen) phase
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