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Gln is essential for activating several of these pathways, particularly the mitogen-activated protein kinases (MAPKs), including Extracellular signal-regulated kinase 1/2 (ERK1/2) and c-Jun N-terminal Kinases 1 and 2 (JNK1/2)

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Your body can't produce it on its own, so you must get it from your diet or through supplementation

10.1097/00003086-199302000-00042 58 KawaiT.MiekiA.OhnoY.UmemuraM.KataokaH.KuritaS.et al (1993)