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A comparison of the clinical efficacies of GLP-1RAs and SGLT-2is o is summarized in Figure 1

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Furthermore, in the gastrocnemius muscle of SOD1 G93A mice, the activities of the TCA cycle enzyme 2-oxoglutarate dehydrogenase (OGDH) were found to be reduced in the late symptomatic phases of the disease, indicating impairments in the TCA cycle pathway (Tefera et al., 2016)

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10.1097/HRP.0000000000000167 61 MillerM

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