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This preservation of mitochondrial integrity may be attributed to the suppression of excessive mitochondrial fission by the upregulation of adipose triglyceride lipase Atgl, the rate-limiting enzyme of triglyceride hydrolysis

Tirzepatide is approved for moderate to severe obstructive sleep apnea in adults with obesity

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It could cause fluctuations in your energy levels

van Bloemendaal et al., 2014), and in right insula, amygdala and left OFC in patients with obesity (van Bloemendaal et al., 2014)

Regarding hunger cues, it can also act on the central nervous system to further suppress appetite and increase satiety signals