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For example, a 2026 meta-analysis published in the British Medical Journal (BMJ) reviewed 37 studies of 9,341 people with excess weight or obesity to compare how much weight they regained in the year after they stopped taking weight-loss medicines or attending behavioural weight-loss programmes

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Prescribers can decide to use a medication off-label because, in their professional judgment, they believe it may offer a benefit to someone

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In addition, it mimics the GIP hormone that influences glucose levels in the body patients tend to feel fuller even when consuming fewer calories