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Initially FDA-approved for the management of type 2 diabetes, these drugs are now a viable solution for weight loss because they mimic the hormone GLP-1 to increase feelings of fullness, slow gastric emptying, and stimulate insulin release, while targeting brain receptors that help reduce cravings and hunger
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In waist circumference, the strongest effect was observed with GLP-1 plus metformin, whereas metformin and myoinositol comparisons remained nonsignificant
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10.1016/j.jconrel.2015.11.032 168
FAQs About GLP-1 and GIP/GLP-1s for Obesity 9 7
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