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A 2018 review article published in the Journal of Clinical and Aesthetic Dermatology found that glutathione may be an effective treatment for hyperpigmentation and skin whitening

High glucose induces apoptosis via upregulation of Bim expression in proximal tubule epithelial cells

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B12 Deficiency and Dermatological Symptoms Patients with a vitamin B12 deficiency may notice dermatological symptoms such as hyperpigmentation, vitiligo, or dry, irritated skin

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