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Although -synuclein is frequently implicated in PD pathogenesis, other proteins such as PTEN induced putative kinase 1 (PINK1), Parkin, DJ-1, leucine-rich repeat kinase 2 (LRRK2) have been strongly linked to familial forms of PD 6,7

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2.2.1 Inclusion criteria Healthy adults, male or female, aged 1865 years Stable medical conditions, including stable hepatic, renal and hematological status confirmed by the laboratory tests

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Appetite score was calculated as the average of each parameter