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(5,6) KPV exerts potent anti-inflammatory effects by modulating key intracellular signaling pathways, including the inhibition of NF-B activation, which plays a central role in controlling the transcription of pro-inflammatory genes

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Mechanism-Based Inhibition of Human Steroid 5-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADPDihydrofinasteride, a Potent Bisubstrate Analog Inhibitor.J.Amer.Chem.Soc.1996,118, 2359-2365 78

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