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However, no single trial has been adequately powered to test heterogeneity of cardiovascular effect for T2DM patients with established CVD compared to patients with T2DM and cardiovascular risk factors only, limiting conclusions of heterogeneity of effect to meta-analyses of CVOT trials completed to date (91)

Type 2 diabetes is commonly managed with lifestyle changes, oral medications, or insulin

These responses work to help the liver maintain its function of detoxifying impurities by neutralizing free radicals produced in the liver and preventing stress which leads to cell damage and contributes to the development of liver diseases

Real-world data for regulatory decision making: challenges and possible solutions for Europe

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