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These associations involve chronic endogenous elevation, but they establish the biological plausibility of concern for long-acting exogenous analogues [8]
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Research Models & Proposed Pathways Evidence Level & Research Limitations Biochemical and cell studies Mechanistic observations and copper-binding experiments
The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline
Moreover, serotonin metabolites (5-hydroxyindoleacetic acid) derived from activated platelets and mast cells in the lung can act as ligands to drive eosinophil recruitment via the chemotactic receptor G protein-coupled receptor 35, exacerbating fungal infections (De Giovanni et al., 2023)
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