tirzepatide allodynia GLP-1 Drugs: New Reports of Dysesthesia and Allodynia: Causes, Management, and the

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Completion of the trials main phase is expected in September 2025, and the 52-week extension (in which participants and investigators remain blinded to treatment assignment) will continue to October 2026

Absolute contraindications Pregnancy and breastfeeding (no injectables, no energy-based devices)

Choline and Methionine are crucial for liver function

Studies confirm that fiber supplementation lasting at least four weeks significantly increases stool frequency and softens stool consistency compared to placebo