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German native Martina Big, 32, who was born with blonde hair and pale skin, has undergone a complete transformation, changing her hair, skin, breasts and name in a bid to become a Black woman

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8 SUMMIT also demonstrated significant improvements in patient-reported outcomes: at 52 weeks, tirzepatide increased KCCQ-CSS, with a between-group mean difference of 6.9 points, and increased 6-minute walk distance, with a between-group mean difference of 18.3 m