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L-carnitine can be directly transformed into TMA via intestinal flora-derived CntA/CntB , and also into -butyrobetaine and betaine, and further converted to TMA through the yeaW/yeaX enzyme system of intestinal flora (36)

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The results showed that among phosphoproteins, 24 were upregulated (FC 1.2) and 52 were downregulated (FC 0.83) in fibroblasts from keloid versus those from adjacent skin (Supplementary Data 1)

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