To put that in perspective, a 10 mg/kg dose in a 250-g rat, scaled allometrically to a 70-kg human using the FDA's body surface area conversion factor of 6.2, translates to roughly 1.6 mg/kg, or 112 mg for a 70-kg person 7
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Conversely, high-fat foods, caffeine, and artificial sweeteners can worsen diarrhea by increasing secretion and motility
An important systemic consequence of AKI is its effects on energy metabolism and redox balance
doi:10.4103/0970-9185.117079