In the most of the studies the primary endpoint is a change in HbA1c from baseline, except for the SURPASS J combo, where the primary endpoint is the number of patients with more than one critical adverse event (69, 70)
Did your doctor perform a gastric emptying diagnostic study
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Adjusting the dosage or switching to a different medication might be necessary in some cases
While injection site reactions appear in the FAERS database for tirzepatide, they are far less frequently reported than gastrointestinal side effects like constipation , diarrhea , and nausea