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Other less common nutrient deficiencies that can occur after gastric bypass surgery include thiamine, zinc, copper and vitamins A and K

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In a murine diet-induced obesity (DIO) model, after 25 days of treatment, results demonstrated: Greater than 30% weight loss when nimacimab was combined with the dual GLP-1/GIP agonist, tirzepatide Nimacimab alone demonstrated 23.5% weight loss, comparable to monlunabant and tirzepatide alone

According to the researchers, retatrutide-treated diabetic rats showed partial preservation of hippocampal and cortical tissue organization compared with untreated diabetic animals

Conversely, discontinuation rates were increased to 28.1% (95% CI 27.7, 28.4) at 1 year and 43.6% (95% CI 43.2, 44.0) at 3 years when using a grace period of 60 days (ESM Table 4)