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Dual GLP-1/glucagon receptor agonists additionally engage pathways that increase energy expenditure and fat oxidation, potentially counteracting metabolic adaptations that limit sustained weight loss
Physiologie der Haustiere
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Joint pain (arthralgia) is not a recognised common class-wide side effect of GLP-1 agonists, with incidence in many trials similar to placebo
Discussion As an essential factor in mitochondrial FA -oxidation, L-carnitine has been used to alleviate fat accumulation-related metabolic syndromes in humans and other mammals for decades 8,9,30