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The results demonstrated that Aloe vera significantly ameliorated ethanol-induced: (1) acute mucosal injury (decrease UI and provide high I%), (2) oxidative stress (reduced gastric MDA and increased GSH), (3) hypergastrinemia and hyperacidity (decreased serum gastrin and increased gastric pH), and (4) pyroptotic cell death (downregulated gastric NLRP3 and GSDMD mRNA expression)

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(2026) Alcohol is not formally contraindicated with GLP-1 medications, but it amplifies nausea, hypoglycemia risk, and dehydration

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Individuals who are pregnant/breastfeeding or may become pregnant while on GLP-1 injections should not take this medication

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