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GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine complexed with Cu(II)) whose endogenous serum levels decline measurably with age

More importantly, glutamine suppression of melanoma oncogenic pathways via a global decrease in H3K4me3 levels can not only cooperate with but also re-sensitize resistant tumours to targeted therapies

doi:10.3389/fneur.2018.00178 Gurvich C, Maller JJ, Lithgow B, Haghgooie S, Kulkarni J

and a short disordered C-terminal domain (CTD), which interacts with intracellular proteins 1,37

The proposed mechanism includes modulation of oxidative stress and mitochondrial biogenesis

PMID: 41209547 References are provided for research reference only