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Action sur la peau En captant les radicaux libres au niveau du derme et de lpiderme, des tudes ont pu confirmer laction du GSH dans la prvention de lapparition des ridules et lamlioration de llasticit cutane

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10.1016/j.cmet.2019.01.020 Summary Keywords xCT transporter, cysteine, lipid peroxides, glutathione, ferroptosis, tumor-resistance Citation Daher B, Vueti M and Pouyssgur J (2020) Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death

Animals treated with DSIP (MCAO + DSIP group) showed a significantly improved performance in the rotarod test compared to vehicle-treated MCAO animals

The ASMT encoded enzyme is also known as hydroxyindole- O -methyltransferase (HIOMT)

ROS can affect mitochondrial DNA which can cause modulations in the synthesis of METC components like adenosine triphosphate (ATP) production as well as the leakage of ROS into the cells cytoplasm ( Although the precise mechanism corresponding to ROS generation related to PD is still unknown, in this review, we summarize the major sources of oxidative stress generated by the DA neurons, like DA metabolism, mitochondrial dysfunction, and neuroinflammation ( Figure 1 )