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DOI: Published online: October 24, 2024 1 Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, Korea 2 Biomedical Research Institute, Pusan National University Hospital, Busan, Korea 3 Department of Biostatistics, Clinical Trial Center, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Corresponding author: Bo Hyun Kim Department of Internal Medicine, Pusan National University School of Medicine, 49 Busandaehak-ro, Mulgeum-eup, Yangsan 50612, Korea E-mail: [email protected] Copyright 2025 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

it was studied by Novo Nordisk and later Helsinn Therapeutics, including a Phase II trial for postoperative ileus, but development was discontinued for lack of efficacy