Schematic of the triple-receptor mechanism: GLP-1 (teal), GIP (blue) and glucagon (amber)
The breakthrough came from creating synthetic versions of these hormones engineered to resist breakdown
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GLP-1 receptor agonist medications are typically considered for type 2 diabetes when other treatments are ineffective or inappropriate, particularly if you have a BMI 35 kg/m with weight-related complications
Psychiatry 6 , e809 (2016)