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Applications in Cellular Senescence Models Cellular senescence is the foundation of organismal aging
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An 18% increase in the mean cellular GSH level was achieved in cultures of the engineered strain supplemented with D-histidine to counter-select cells with high GAP1 expression (i.e
Aging is associated with a decrease in glutathione activity, which can result in increased oxidative stress
[10] [12] High-dose ascorbic acid may diminish the therapeutic effects of certain chemotherapeutic agents, such as bortezomib, due to its antioxidant properties
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