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Glutathione injections are generally safe, but some individuals may experience mild side effects such as pain, redness, or swelling at the injection site, as well as occasional nausea or headaches
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An advanced comprehension of the basic biology of CHAC enzymes, derived from rigorous biochemical and genetic studies, is therefore a prerequisite for their rational therapeutic exploitation
doi: 10.3389/fendo.2023.1085041 Received 31 October 2022 Accepted 26 January 2023 Published 07 February 2023 Volume 14 - 2023 Edited by Tarunveer Singh Ahluwalia, Steno Diabetes Center Copenhagen (SDCC), Denmark Reviewed by Piotr Konopelski, Medical University of Warsaw, Poland
On the other hand, overexpression of Nrf2 (transcriptional regulator of seleno-GPxs) contributed to the increase in the radioresistance and stemness in glioma stem cells (GSCs) by upregulating GPx1 and decreasing the cellular ROS level
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