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To avoid sleeplessness, do not consume within 4 hours of bedtime

Hepatic and Metabolic Benefits A MAFLD/MASLD (metabolic dysfunction-associated steatotic liver disease) sub-study of the Phase 2 obesity trial reported that over 85% of participants on the highest retatrutide doses achieved more than 30% reduction in liver fat content measured by MRI, with many reaching complete resolution of steatosis

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an effect that may be due to compensatory mechanisms in response to the marked reduction of body weight after chronic treatment with GLP1/E

MASH can lead to scarring of the liver and cirrhosis, and it is one of the most common reasons for liver transplants

Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors, currently under clinical investigation and not yet approved by the MHRA or EMA