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By selectively inhibiting NNMT an enzyme central to energy regulation and fat metabolism this compound has demonstrated, in preclinical studies, the capacity to elevate intracellular NAD and SAM levels, suppress lipid accumulation in adipocytes, and reduce white adipose tissue mass in diet-induced obese mouse models

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Food and Drug Administration's Pharmacy Compounding Advisory Committee reviewed AOD-9604 alongside other unapproved peptides and recommended against allowing the compound to be used in 503A pharmacy compounding