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In the PIONEER 1 trial , which assessed Rybelsus as monotherapy in treatment-nave patients, both the 7 mg and 14 mg doses demonstrated statistically significant HbA1c reductions compared to placebo

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doi: 10.1159/000530456 105 HuszarDLynchCAFairchild-HuntressVDunmoreJHFangQBerkemeierLR