Therefore, in this study, we hypothesize that Ex-4 is neuroprotective by reducing BBB damage of EBI through downregulation of downstream targets, NF-B and MMP-9 via phosphorylation of AMPK (p-AMPK) after experimental SAH model in rats
SOD converts superoxide radicals into hydrogen peroxide, which is then detoxified by CAT and GPx, ensuring effective cellular protection against oxidative damage (32, 33)
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