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The pancreatic lipase inhibitor orlistat loses weight by inhibiting pancreatic lipase activity, which in turn inhibits the breakdown and absorption of fat from food

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Obese asthmatics are unique in that they are often steroid-resistant, and it is possible that mechanistic differences in obese asthmatics and weight loss with GLP1 may have pleomorphic effects on inflammation beyond just weight loss, the study authors noted

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The Practical Takeaway If you're having symptoms and your B12 is high, here's how to think about it: First, separate the two questions