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zellikle C, E ve B6 vitaminleri ile selenyum gibi besin unsurlarnn yetersiz alm, vcudun glutatyon retimi iin gerekli yaptalarn salayamamasna neden olabilir

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Notably, GSH binding motif is not conserved among the other seleno-GPxs (GPx2, GPx3, GPx4, and GPx6) justifying their abilities to use wide variety of thiols like cysteine, protein thiols, mercaptoethanol, and dithiothreitol in addition to GSH as reducing equivalent for the catalysis [8, 17, 18]

Your colon has more time to absorb water from stool, making it harder and more difficult to pass

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