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Research suggests that it also contributes to cytoprotective processes by enhancing cellular resistance to chemical, mechanical, or ischemic stress
Statements Author contributions DX and RL conceived the study and took responsibility for the integrity of the study
On the one hand, the administration of fructo-oligosaccharides to diet-induced obese mice decreased their motivation for sucrose pellets as compared to diet-induced obese mice, after an overnight fasting, suggesting a worsening of their wanting component of the reward (Delbes et al., 2018)
& Brown, G
That uncertainty is precisely why it remains an interesting research tool rather than a settled one, and it is stated plainly here rather than papered over with confident mechanism claims
A 2021 study in Biochemical Pharmacology examining AHK-Cu's effect on TNF- and IL-6 expression in LPS-stimulated macrophages used 300mcg administered intraperitoneally, achieving statistically significant reductions in pro-inflammatory markers at 4, 8, and 12 hours post-administration
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