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ICH Q3C(R9) provides the standard framework for classifying and controlling residual solvents

Reported side effects include water retention, flushing, headache, tingling in the extremities, elevated IGF-1 levels, impaired glucose tolerance, and injection site reactions including pain and infection risk

### Market Dynamics and Analyst Outlook The global weight-loss drug market is experiencing exponential growth, with projections reaching nearly $196 billion by 2036, driven by increasing obesity rates and the recognition of obesity as a chronic disease

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Tirzepatide once weekly for the treatment of obesity

doi: 10.1186/S12933-020-01211-4/FIGURES/1 124 KaragiannisTBekiariETsapasA