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International Journal of Pharmaceutical Sciences

PUFA (Polyunsaturated fatty acid)-rich diets increase the production of PUFA-containing phospholipids (PLs), which promote tumor ferroptosis [30]

For instance, ferroptosis, an emerging form of cell death, is influenced by the systemic regulation of related genes, such as GPX4, which can affect multiple organ systems, particularly vital organs like the liver and heart

Furthermore, activation of the transcription factor c-JUN diacylglycerol kinase (DGKA) leads to the recruitment of c-JUN N-terminal kinase to c-JUN and enhances the expression of the cell cycle regulator WEE1 under cisplatin stimulation, ultimately leading to platinum resistance in ovarian cancer (57)

therefore, opportunistic pathogens could selectively enrich in fecal microflora of COVID-19 patients 249,250

This improves the patients quality of life