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Until these results are available, GLP-1 receptor agonists with established cardiovascular benefits (liraglutide, semaglutide, dulaglutide) are preferred by ADA guidelines for patients with established atherosclerotic cardiovascular disease

Some Medicare plans will begin covering Wegovy for weight loss in July 2026, and some already cover it for other indications

Packer is the lead and corresponding author of the study reporting the results that was simultaneously in the Journal of the American College of Cardiology ( JACC ) with Packers presentation of the data at the ACC meeting in Chicago

There is a slightly higher risk of a low blood sugar episode if you combine oral semaglutide with injectable insulin or drugs that trigger insulin secretion (sulfonylureas)

Tirzepatide is dosed once weekly, and crossing time zones does not require a dose adjustment or schedule change

Science 2002;297:353-6