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This escalation approach is standard across GLP-1 class compounds and serves to improve gastrointestinal tolerability

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For weight management, treatment duration may depend on achievement and maintenance of weight loss goals, with some patients requiring long-term therapy to maintain weight reduction while others may successfully transition to lifestyle modifications alone after achieving target weight

Severity of deficiency: if your levels were very low, it may take several doses to fully restore your tissues, or you may feel a dramatic early difference because your body was so depleted

Some people become B12 deficient due to other reasons such as a medical condition or alcohol misuse