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Among participants in those trials who had been taking semaglutide or tirzepatide, the study found a mean weight regain of 9.69 kg (95% CI 5.7813.60) over the follow-up period (Berg et al., 2025)
If possible, use tools like bioelectrical impedance or periodic DEXA scans to determine whether your weight loss comes from fat or muscle
The most effective ways to increase GLP-1 naturally are through diet and lifestyle
Diabet Med 2018;35:14349
Relationship of glucose regulation to changes in weight: a systematic review and guide to future research
Weeks 17 through 20 at 2.4mg: 9.6mg total
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