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Overactivated HER2 signaling results in increased HIF-1 and VEGF expression, which in turn activate the downstream kinase FKBP-rapamycin-associated protein (FRAP), therefore contributing to tumor progression by mediating angiogenesis and metabolic adaptation (221)

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Vitamin B12 Injection is often supplied as cyanocobalamin injection 1000 mcg/mL, also written as 1,000 mcg per mL