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One single-center, double-blind, randomized, placebo-controlled crossover study enrolled 24 participants between the ages of 22 and 58 years old with mass indexes (BMI) ranging from normal weight (18.5) to obese (31.8)

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In addition, by carefully excluding patients with preexisting depression or recent antidepressant use, the design minimizes potential confounding by indication [] The clinical implications of this study are multifaceted

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