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2021;184(10):2715-2732.e23
In a rat model of spinal nerve ligation (SNL), exenatide significantly enhanced the expression of M2 microglial markers, including IL-10, IL-4, Arg1, and CD206, in both spinal microglia and primary cultured microglia [63]
These data are line with pharmacodynamic results from other studies with SAR425899 14 , confirming the drug to be a potent GLP-1 receptor agonist
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