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Tirzepatide is a dual GLP-1 and GIP receptor agonist, which is part of why SURMOUNT-1 participants lost more weight on average than STEP 1 participants lost on semaglutide, though the two trials were not run head-to-head in the same population

Additionally, it is important to note that as a result of the lack of clinical data on this novel agent, further high-quality clinical studies are needed in the future

The standard protocol begins with a low dose and increases gradually over 16 to 20 weeks, allowing your body to adapt while tracking tolerance and effectiveness