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Therefore, loss of TKT in adipose tissues alleviates high fat diet (HFD)-induced obesity, leading to reduced hepatic steatosis and improved insulin sensitivity (24)

Clinical studies have shown that both medications can result in significant weight loss for individuals with type 2 diabetes

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However, those with certain rare conditions (like Lebers disease) should consult their doctor before supplementing

If regulatory submissions proceed as expected, the earliest plausible timeline for a market authorisation decision in the UK or Europe would be 2026 or 2027 though this is subject to the pace of regulatory review, the completeness of the submission package, and any additional data requests from the MHRA or EMA