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TB500 (molecular weight: 889.0 g/mol) is a short peptide fragment derived from thymosin beta-4, a protein involved in cell migration and angiogenesis (new blood vessel formation) in experimental systems

4,10 It has been proposed that rheumatoid nodules tend to occur in regions that are subject to repeat microtrauma. 11 The area at the center of the vocal folds is subject to the greatest shearing forces during vibration

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Parts of the computational results of this work have been achieved using the Life Science Compute Cluster of the University of Vienna