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An extension analysis of the original STEP-1 trial (n = 327) aimed to observe weight gain and cardiometabolic effects after withdrawal of both SC semaglutide and lifestyle interventions following 68 weeks of therapy

Those with the normal neurabin levels intact experienced seizures lasting for up to 30 minutes and about 10% of the mice died shortly afterward

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Acknowledgements We thank members of the Li lab for constructive discussions